Research

Active research across diabetes, brain health, and therapeutic discovery

Joseph Schulz's ORCID-indexed work spans pancreatic biology, Alzheimer's disease models, computational drug discovery, smart health technology, and medicinal chemistry.

8 ORCID-indexed works

2019-2026 publication record with a focus on prevention, cellular biology, computational modeling, and translational health tools.

Focus areas

Research that supports the mission

01

Diabetes and pancreatic biology

Work on pancreatic tissue, endocrine cell formation, and metabolism connects the research record directly to the biology behind diabetes prevention.

02

Brain health and Alzheimer's modeling

Stem-cell disease modeling creates a bridge between Type III Diabetes education, cognitive health, and future intervention strategies.

03

Computational therapeutic discovery

Molecular dynamics, protein modeling, PROTACs, and targeted degradation point toward modern tools for asking better biomedical questions.

04

Health technology and daily systems

Smart-home and wellness-technology work supports Mindful Diabetes' practical belief that healthier environments can make prevention easier.

Publication record

Selected works from ORCID

Each article below links to its DOI so visitors can move from the Mindful Diabetes overview to the original research source.

2026 Computational methods

SSRN preprint / European Journal of Medicinal Chemistry record

PyMACS: A Python-Based Automation Suite for GROMACS Molecular Dynamics Setup, Simulation, and Analysis

PyMACS turns a technically demanding molecular dynamics workflow into a more reproducible, scriptable pipeline. For Mindful Diabetes, this kind of computational infrastructure matters because it supports faster, cleaner exploration of biological targets and therapeutic hypotheses.

Molecular dynamics Automation Drug discovery
2025-10-28 Journal article

Scientific Reports

PRosettaC outperforms AlphaFold3 for modeling PROTAC ternary complexes

This study compares structure-prediction approaches for PROTAC ternary complexes, a difficult problem in targeted protein degradation. It shows active work at the intersection of computational biology, therapeutic design, and model evaluation.

PROTACs Protein modeling AI comparison
2024-08-07 Journal article

International Journal of Smart Technologies

Broad Perspective of Smart Home Technology in 2024

This article surveys the modern smart-home landscape and its role in everyday support systems. That perspective connects directly to prevention work: better environments can make healthy routines easier to start and sustain.

Smart homes Health technology Daily living
2024-01 Journal article

Drug Discovery Today

Targeted degrader technologies as prospective SARS-CoV-2 therapies

This review explores how targeted protein degradation could become part of antiviral therapeutic development. It reflects a broader research focus on translating molecular mechanisms into practical treatment strategies.

Targeted degradation Antivirals Therapeutic strategy
2023-11 Journal article

Cell Metabolism

Dynamic scRNA-seq of live human pancreatic slices reveals functional endocrine cell neogenesis through an intermediate ducto-acinar stage

This pancreatic-slice study uses live human tissue and single-cell sequencing to investigate endocrine cell formation. It is especially relevant to diabetes research because it examines cellular plasticity in the organ central to insulin biology.

Pancreatic biology Single-cell RNA-seq Endocrine cells
2023-10-18 Journal article

SCIREA Journal of Biology

Embryonic adipose development and consequences in later life

This work looks at adipose development early in life and how developmental events may shape later health. It supports the Mindful Diabetes emphasis on prevention by looking upstream, before metabolic problems become entrenched.

Adipose biology Development Metabolism
2021-05-26 Journal article

Stem Cells International

The Potential of Induced Pluripotent Stem Cells to Treat and Model Alzheimer's Disease

This article reviews how induced pluripotent stem cells can help model Alzheimer's disease and support therapeutic discovery. It sits close to Mindful Diabetes' core mission by connecting brain health, disease modeling, and future intervention pathways.

Alzheimer's disease iPSCs Disease modeling
2019-04-26 Journal article

Journal of Natural Products

Concise Modular Synthesis of Thalassotalic Acids A-C

This chemistry paper focuses on modular synthesis of thalassotalic acids, adding a foundational medicinal-chemistry thread to the research portfolio. It rounds out the publication record with hands-on chemical synthesis experience.

Natural products Chemical synthesis Medicinal chemistry

Why it matters

Research gives Mindful Diabetes a stronger foundation

Our public education, prevention messaging, and wellness tools are stronger when they are connected to real research experience and a continuing publication record.

Read the guide